Description

2-(Piperidin-1-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecular architectures through versatile cross-coupling reactions, particularly the Suzuki-Miyaura reaction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex pyridine-piperidine scaffolds.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronate ester group makes it an ideal reagent for palladium-catalyzed cross-coupling with aryl/heteroaryl halides, enabling efficient carbon-carbon bond formation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Ligand and Catalyst Development: The nitrogen-containing heterocycle can be utilized to develop novel ligands for catalysis or as a core structure in functional materials.
• Chemical Biology Probes: Serves as a building block for creating molecular probes and tools used in biochemical and cellular research.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs or conductive polymers, where precise molecular engineering is required.

Basic Information

Product Name	2-(Piperidin-1-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1402166-06-6
Molecular Formula	C16H25BN2O2
Molecular Weight	288.20 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(piperidin-1-yl)pyridine; 2-Piperidin-1-yl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(1-Piperidinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(Pinacolatoboryl)-2-(piperidin-1-yl)pyridine; 2-Piperidino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; CAS 1402166-06-6
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2-(Piperidin-1-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications and test results are available upon request, providing full traceability and supporting your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.