Description

2-((3Ar,4S,6R,6As)-6-Amino-2,2-Dimethyltetrahydro-3Ah-Cyclopenta[D][1,3]Dioxol-4-Yloxy)Ethanol Oxalate is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined cyclopentane-fused dioxolane structure. This compound matters for its critical role as a key chiral building block in the synthesis of novel nucleoside analogs and other complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in antiviral, anticancer, and other therapeutic development programs requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer therapies.
• Antiviral Drug Development: Used in research and production of potential therapeutics targeting viruses such as hepatitis and herpes.
• Protease Inhibitor Synthesis: Acts as a key component in constructing complex molecules for protease inhibitor development.
• Chemical Biology Research: Employed as a molecular probe or building block in studying enzyme mechanisms and biological pathways.
• Process Chemistry & Scale-Up: Utilized in process development and optimization for the commercial manufacturing of complex APIs.
• Custom Synthesis: Provided for contract research organizations (CROs) and pharmaceutical companies requiring bespoke, high-purity intermediates.

Basic Information

Product Name	2-((3Ar,4S,6R,6As)-6-Amino-2,2-Dimethyltetrahydro-3Ah-Cyclopenta[D][1,3]Dioxol-4-Yloxy)Ethanol Oxalate
CAS No.	1402150-30-4
Molecular Formula	C12H21NO7
Molecular Weight	291.30 g/mol
Synonyms	6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxyethanol oxalate; (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxyethanol oxalate; 2-[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyl-3a,4,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxyethanol oxalate; Oxalic acid compound with 2-[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-3a,4,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxyethanol (1:1); Cyclopentane-fused dioxolane amino alcohol oxalate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-((3Ar,4S,6R,6As)-6-Amino-2,2-Dimethyltetrahydro-3Ah-Cyclopenta[D][1,3]Dioxol-4-Yloxy)Ethanol Oxalate is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.