Description

4-(1,3-Dioxolan-2-Yl)Phenylboronic Acid is a specialized organoboron compound featuring a phenylboronic acid moiety protected with a 1,3-dioxolane group. This structure is critical as a versatile building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the construction of complex biaryl and heterobiaryl systems. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific biaryl architectures.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating advanced organic electronic materials and display components.
• Polymer Chemistry: Employed in the synthesis of functionalized polymers and dendrimers with tailored properties.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and sensors that leverage boronic acid-diol interactions.
• Academic & Process R&D: A valuable reagent for methodological development and scaling new synthetic routes in research laboratories.

Basic Information

Product Name	4-(1,3-Dioxolan-2-Yl)Phenylboronic Acid
CAS No.	1401222-65-8
Molecular Formula	C11H13BO4
Molecular Weight	220.03 g/mol
Synonyms	[4-(1,3-Dioxolan-2-yl)phenyl]boronic acid; 2-[4-(Dihydroxyboryl)phenyl]-1,3-dioxolane; 4-(1,3-Dioxolan-2-yl)benzeneboronic acid; 4-(2-Dioxolanyl)phenylboronic Acid; 4-(1,3-Dioxolan-2-yl)phenyl-B(OH)2; B-[4-(1,3-Dioxolan-2-yl)phenyl]boronic acid; 4-(2,2-Dimethyl-1,3-dioxolan-4-yl)phenylboronic acid (related protected form); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-(1,3-Dioxolan-2-Yl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.