Description

1-Boc-2,3-Dihydropyrrole-4-Boronic Acid, Pinacol Ester is a high-value, protected boronic ester building block essential for modern synthetic organic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the precise and efficient construction of complex nitrogen-containing heterocycles, which are pivotal scaffolds in pharmaceutical discovery and advanced material science. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional molecules. CAS No. 1401165-14-7.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing dihydropyrrole or pyrrole motifs for oncology, CNS, and anti-infective therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid ester partner for palladium-catalyzed coupling with aryl/heteroaryl halides to form carbon-carbon bonds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex heterocyclic structures.
• Material Science & OLED Development: Employed in the creation of organic semiconductors, light-emitting materials, and other functional materials where specific electronic properties are needed.
• Chemical Biology & Probe Synthesis: Utilized for labeling and modifying biomolecules or creating activity-based probes for target identification and validation.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic pathways in academic and CRO laboratory settings.

Basic Information

Product Name	1-Boc-2,3-Dihydropyrrole-4-Boronic Acid, Pinacol Ester
CAS No.	1401165-14-7
Molecular Formula	C15H26BNO4
Molecular Weight	295.19 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-pyrrole-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-pyrrole-1-carboxylate; 1-Boc-2,3-dihydro-1H-pyrrole-4-boronic acid pinacol ester; N-Boc-2,3-dihydropyrrole-4-boronic acid pinacol ester; 1-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-pyrrole; 1-Boc-2,3-dihydropyrrole-4-Bpin
EINECS	Contact for details

Quality Control

Our 1-Boc-2,3-Dihydropyrrole-4-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and process chemistry. All products undergo rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.