Description

2-(3-Ethoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl couplings.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, including OLEDs, OFETs, and conductive polymers.
• Chemical Research & Development: An indispensable reagent for medicinal chemists and process chemists exploring new synthetic routes and optimizing coupling reactions.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Fine Chemical Production: Used in the manufacture of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	2-(3-Ethoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1400274-77-2
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	3-Ethoxyphenylboronic acid pinacol ester; (3-Ethoxyphenyl)boronic acid pinacol ester; 3-Ethoxybenzeneboronic acid pinacol ester; 3-Ethoxyphenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1,3,2-Dioxaborolane, 2-(3-ethoxyphenyl)-4,4,5,5-tetramethyl-; Pinacol (3-ethoxyphenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-(3-Ethoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent moisture absorption and degradation. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.