Description

1-(2-Fluoro-Phenoxy)-Cyclopropanecarboxylic Acid is a high-value fluorinated cyclopropane derivative, a key building block in modern synthetic chemistry. Its core value lies in its unique molecular scaffold, which combines a fluorinated aromatic ether with a strained cyclopropane carboxylic acid moiety, enabling precise structural modifications in complex molecule synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom and cyclopropane ring enhance biological activity and environmental stability.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Precursor: Employed in the research and development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probe: Utilized as a molecular scaffold for designing chemical probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	1-(2-Fluoro-Phenoxy)-Cyclopropanecarboxylic Acid
CAS No.	1399659-67-6
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	2-Fluorophenoxycyclopropanecarboxylic Acid; 1-(2-Fluorophenoxy)cyclopropane-1-carboxylic Acid; Cyclopropanecarboxylic acid, 1-(2-fluorophenoxy)-; 1-(o-Fluorophenoxy)cyclopropanecarboxylic Acid; 1-(2-Fluorophenoxy)cyclopropanecarboxylic Acid; 1399659-67-6; 2-Fluoro-1-cyclopropanecarboxyphenoxy; (2-Fluorophenoxy)cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-Phenoxy)-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and compliance with REACH regulations ensures a reliable supply of high-purity material for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.