Description

2-(2-(4-Bromo)Prop-1-En-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block, specifically a vinyl boronic ester, designed for advanced cross-coupling reactions. Its core value lies in enabling the precise and efficient synthesis of complex organic molecules, which is critical for research and development in fine chemical and pharmaceutical manufacturing. This compound is essential for medicinal chemists and process development scientists working on new drug candidates, agrochemicals, and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between the vinyl group and aryl or heteroaryl halides, enabling the construction of complex molecular scaffolds.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), particularly those requiring substituted styrene or diene motifs.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where controlled vinyl functionalization is required.
• Chemical Biology Probes: Useful for tagging biomolecules or creating activity-based probes due to its reactive vinyl boronate handle.
• Catalyst and Ligand Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Item	Details
Product Name	2-(2-(4-Bromo)Prop-1-En-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1398771-27-1
Molecular Formula	C13H22BBrO2
Molecular Weight	301.03 g/mol
Synonyms	4-Bromostyrene pinacol boronic ester; (2-(4-Bromophenyl)ethene-1,1-diyl)bis(2-methylpropane-2,1-diyl) boronate; 2-(2-(4-Bromophenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromostyrene pinacol ester; 4-Bromostyrylboronic acid pinacol ester; 1-(4-Bromophenyl)vinylboronic acid pinacol ester; (E)-2-(2-(4-Bromophenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (Z)-2-(2-(4-Bromophenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(2-(4-Bromo)Prop-1-En-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.