Description

4,4,5,5-Tetramethyl-2-(2-(m-Tolyl)Prop-1-En-1-Yl)-1,3,2-Dioxaborolane is a high-purity organoboron reagent, specifically a pinacol boronic ester, valued for its stability and reactivity in advanced synthetic chemistry. This compound is essential for facilitating key carbon-carbon bond-forming reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for introducing the (m-tolyl)propenyl moiety into target molecules, widely used in pharmaceutical intermediate synthesis.
• Pharmaceutical Research & Development: Serves as a critical precursor in the discovery and process development of new drug candidates, particularly for creating biaryl and styrenyl structures.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides where specific aromatic and olefinic components are required.
• Materials Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting materials, and other functional polymers.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or creating activity-based probes for research.
• Catalyst and Ligand Preparation: Acts as an intermediate in the synthesis of sophisticated ligands for transition metal catalysis.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2-(m-Tolyl)Prop-1-En-1-Yl)-1,3,2-Dioxaborolane
CAS No.	1398771-23-7
Molecular Formula	C18H27BO2
Molecular Weight	286.22 g/mol
Synonyms	2-(2-(3-Methylphenyl)prop-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-(3-Methylphenyl)prop-1-en-1-yl)boronic acid pinacol ester; m-Tolylpropenyl Pinacol Boronate; (2-(m-Tolyl)prop-1-en-1-yl)boronic acid pinacol ester; Boronic acid, B-[2-(3-methylphenyl)-1-propen-1-yl]-, 1,1-dimethylethyl ester; CAS 1398771-23-7; Pinacol (2-(3-methylphenyl)prop-1-en-1-yl)boronate
EINECS	Contact for details

Quality Control

Our production of 4,4,5,5-Tetramethyl-2-(2-(m-Tolyl)Prop-1-En-1-Yl)-1,3,2-Dioxaborolane adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.