Description

Methyl 4-(Trifluoromethyl)-1H-Pyrrole-2-Carboxylate is a high-value fluorinated pyrrole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique reactivity and electronic properties imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced biological activity and material characteristics. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability, lipophilicity, and overall efficacy.
• Material Science Research: Employed as a precursor for functional materials, including organic semiconductors, liquid crystals, and advanced polymers, due to its electron-withdrawing characteristics.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for designing molecular probes, enzyme inhibitors, and labeling reagents in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Methyl 4-(Trifluoromethyl)-1H-Pyrrole-2-Carboxylate
CAS No.	1398113-33-1
Molecular Formula	C7H6F3NO2
Molecular Weight	193.12 g/mol
Synonyms	Methyl 4-(trifluoromethyl)-1H-pyrrole-2-carboxylate; 1H-Pyrrole-2-carboxylic acid, 4-(trifluoromethyl)-, methyl ester; Methyl 4-trifluoromethyl-1H-pyrrole-2-carboxylate; 4-(Trifluoromethyl)-1H-pyrrole-2-carboxylic acid methyl ester; 2-Carbomethoxy-4-trifluoromethylpyrrole
EINECS	Contact for details

Quality Control

Our Methyl 4-(Trifluoromethyl)-1H-Pyrrole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.