Description

1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl] -Cyclopentanecarbonitrile is a high-value boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its ability to introduce complex aromatic and alicyclic motifs.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and as a scaffold for functional materials.
• Polymer Chemistry: Incorporated into specialty polymers to modify thermal stability, optical properties, or mechanical strength.
• Academic & Contract Research: A vital reagent for methodology development and the synthesis of complex natural product analogs in research laboratories.

Basic Information

Product Name	1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl] -Cyclopentanecarbonitrile
CAS No.	1396776-57-0
Molecular Formula	C18H24BNO2
Molecular Weight	297.20 g/mol
Synonyms	4-(1-Cyanocyclopentyl)phenylboronic acid pinacol ester; 4-(Cyclopentanecarbonitrile-1-yl)phenylboronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopentanecarbonitrile; (4-(1-Cyanocyclopentyl)phenyl)boronic acid pinacol ester; B-[4-(1-Cyanocyclopentyl)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl] -Cyclopentanecarbonitrile adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is fully characterized by NMR (1H, 13C, 11B), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.