Description

3-Methylbenzofuran-5-Boronic Ester is a high-purity, versatile boronic ester derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers, due to the benzofuran scaffold.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of molecular probes and sensors.
• Catalyst Ligand Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	3-Methylbenzofuran-5-Boronic Ester
CAS No.	1396753-10-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylbenzofuran; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzofuran; 3-Methylbenzofuran-5-boronic acid pinacol ester; 3-Methyl-5-boronic ester benzofuran; Pinacol 3-methylbenzofuran-5-boronate
EINECS	Contact for details

Quality Control

Our 3-Methylbenzofuran-5-Boronic Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.