Description

1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Cyclopropanecarboxylic Acid Methyl Ester is a high-purity boronic ester derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its role as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and conjugated systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing cyclopropane and biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aromatic coupling.
• Material Science Research: Serves as a precursor for organic electronic materials, such as those used in OLEDs, OFETs, and photovoltaic cells.
• Chemical Synthesis & Catalysis: A reliable reagent in academic and industrial laboratories for Pd-catalyzed cross-coupling reactions to create complex molecular architectures.
• Ligand and Catalyst Development: Useful for constructing sophisticated ligand frameworks for transition metal catalysis.
• Life Sciences & Diagnostics: Potential intermediate for synthesizing probes, tags, and other tools used in biochemical research and diagnostic assays.

Basic Information

Product Name	1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Cyclopropanecarboxylic Acid Methyl Ester
CAS No.	1396007-85-4
Molecular Formula	C17H23BO4
Molecular Weight	302.18 g/mol
Synonyms	Methyl 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanecarboxylate; [4-(Methoxycarbonyl)cyclopropyl]phenylboronic acid pinacol ester; 4-(Methoxycarbonylcyclopropyl)phenylboronic acid pinacol ester; Cyclopropanecarboxylic acid, 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-, methyl ester; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Cyclopropanecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) and handle it in a moisture-controlled environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.