Description

B-(3,6-Dihydro-2H-Thiopyran-4-Yl)Boronic Acid CAS NO 1395285-52-5 is a specialized organoboronic acid derivative featuring a thiopyran ring, serving as a versatile building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex sulfur-containing molecules through reliable cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

This thiopyran-substituted boronic acid is a key synthetic intermediate with applications across advanced chemical synthesis.

• Pharmaceutical Intermediate: Crucial for Suzuki-Miyaura cross-coupling reactions in the synthesis of novel drug candidates, particularly those targeting CNS and oncology.
• Agrochemical Research: Used to create new sulfur-heterocyclic compounds with potential herbicidal or fungicidal activity.
• Material Science Precursor: Acts as a monomer or building block for developing advanced organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways involving sulfur metabolism.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke, high-value fine chemicals and APIs.

Basic Information

Product Name	B-(3,6-Dihydro-2H-Thiopyran-4-Yl)Boronic Acid
CAS No.	1395285-52-5
Molecular Formula	C9H13BO2S
Molecular Weight	196.07 g/mol
Synonyms	(3,6-Dihydro-2H-thiopyran-4-yl)boronic acid; 4-Borono-3,6-dihydro-2H-thiopyran; B-(3,6-Dihydro-2H-thiopyran-4-yl)boronic acid; 3,6-Dihydro-2H-thiopyran-4-ylboronic acid; Thiopyran-4-ylboronic acid (dihydro); 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-thiopyran (pinacol ester precursor)
EINECS	Contact for details

Quality Control

Our B-(3,6-Dihydro-2H-Thiopyran-4-Yl)Boronic Acid is manufactured under strict quality systems. Each batch is subjected to rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.