Description

2-(2,6-Difluoro-4-Isopropoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters because it enables precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing difluorophenyl and isopropoxy motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-boronate components.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura cross-coupling reactions in academic and industrial R&D laboratories.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts.
• Fine Chemical Production: Integral for the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-(2,6-Difluoro-4-Isopropoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1395282-52-6
Molecular Formula	C₁₅H₂₁BF₂O₃
Molecular Weight	298.14 g/mol
Synonyms	2,6-Difluoro-4-isopropoxyphenylboronic acid pinacol ester; 4-Isopropoxy-2,6-difluorophenylboronic acid pinacol ester; (2,6-Difluoro-4-isopropoxyphenyl)boronic acid pinacol ester; 2-(2,6-Difluoro-4-(propan-2-yloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1395282-52-6; Difluoro-isopropoxyphenyl-Bpin; IsopropoxydifluorophenylBPin
EINECS	Contact for details

Quality Control

Every batch of our 2-(2,6-Difluoro-4-Isopropoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality commitment includes comprehensive analysis via NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.