Description

2-(2,6-Dimethyl-3,6-Dihydro-2H-Pyran-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules. Its unique pyran-substituted structure offers distinct reactivity for diversifying chemical libraries.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring complex aryl-aryl bond formation.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Facilitates the synthesis of boron-containing molecular probes for diagnostic and imaging applications.
• Academic & Process Chemistry: A versatile reagent for methodological development and scaling up synthetic routes in academic and industrial R&D laboratories.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing novel ligands and organometallic catalysts.

Basic Information

Product Name	2-(2,6-Dimethyl-3,6-Dihydro-2H-Pyran-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1394909-88-6
Molecular Formula	C15H25BO3
Molecular Weight	264.17 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-(2,6-dimethyl-3,6-dihydro-2H-pyran-4-yl)-1,3,2-dioxaborolane; 2-(2,6-Dimethyl-3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,6-Dimethyl-3,6-dihydro-2H-pyran-4-boronic acid pinacol ester; (2,6-Dimethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid pinacol ester; Dihydro-2H-pyran-4-boronic acid pinacol ester derivative; CAS 1394909-88-6
EINECS	Contact for details

Quality Control

Our 2-(2,6-Dimethyl-3,6-Dihydro-2H-Pyran-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.