Description

Ethyl 5-Borono-1-Naphthoate is a specialized boronic ester derivative of naphthoic acid, serving as a key synthetic intermediate in modern organic chemistry. Its primary value lies in its utility as a versatile building block for constructing complex molecules via cross-coupling reactions, particularly Suzuki-Miyaura couplings. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require high-purity intermediates for developing active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting complex aromatic and heterocyclic structures.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable boronic ester coupling partner for the formation of carbon-carbon bonds, a fundamental step in medicinal and process chemistry.
• Organic Electronic Materials: Used in the research and development of organic semiconductors, light-emitting diodes (OLEDs), and other advanced functional materials requiring precise naphthalene-based architectures.
• Ligand and Catalyst Synthesis: Employed as a building block for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and herbicides with novel modes of action.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	Ethyl 5-Borono-1-Naphthoate
CAS No.	1394900-71-0
Molecular Formula	C₁₃H₁₃BO₄
Molecular Weight	244.05 g/mol
Synonyms	5-Borono-1-naphthoic acid ethyl ester; Ethyl 5-borononaphthalene-1-carboxylate; 1-Naphthoic acid, 5-borono-, ethyl ester; 5-(Ethoxycarbonyl)naphthalen-1-ylboronic acid; 1-Carbethoxy-5-borononaphthalene; 5-Carbethoxynaphthalen-1-ylboronic acid; Boronic acid, B-[5-(ethoxycarbonyl)-1-naphthalenyl]-
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Borono-1-Naphthoate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development as well as scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or NMR), identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.