Description

(2,2-Difluoroethyl)(Propan-2-Yl)Amine Hydrochloride is a high-purity, specialty organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique difluoroethyl and isopropylamine motifs are highly valuable. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the fluorine atoms for enhanced biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for electronics and material science applications.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for exploratory chemistry and method development projects.

Basic Information

Product Name	(2,2-Difluoroethyl)(Propan-2-Yl)Amine Hydrochloride
CAS No.	1394768-25-2
Molecular Formula	C5H12ClF2N
Molecular Weight	159.60 g/mol
Synonyms	N-(2,2-Difluoroethyl)-N-isopropylamine hydrochloride; N-Isopropyl-2,2-difluoroethylamine hydrochloride; 1-(2,2-Difluoroethyl)(propan-2-yl)amine hydrochloride; 2,2-Difluoro-N-isopropylethanamine hydrochloride; Isopropyl(2,2-difluoroethyl)amine HCl; Propan-2-yl(2,2-difluoroethyl)azanium chloride
EINECS	Contact for details

Quality Control

Our (2,2-Difluoroethyl)(Propan-2-Yl)Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.