Description

1-Methyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Imidazole CAS NO 1394374-23-2 is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is a critical building block in modern organic synthesis, enabling efficient cross-coupling reactions for constructing complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly in medicinal chemistry.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of novel active pharmaceutical ingredients (APIs), especially those containing imidazole and biaryl motifs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require specific aryl-boronate intermediates.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is required.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	1-Methyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Imidazole
CAS No.	1394374-23-2
Molecular Formula	C16H21BN2O2
Molecular Weight	284.16 g/mol
Synonyms	1-Methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazole; 2-(4-(1-Methyl-1H-imidazol-2-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(1-Methylimidazol-2-yl)phenylboronic acid pinacol ester; 1-Methyl-2-(4-(pinacolatoboryl)phenyl)-1H-imidazole; 2-(4-(1-Methyl-1H-imidazol-2-yl)phenyl)-1,3,2-dioxaborinane-4,4,5,5-tetramethyl
EINECS	Contact for details

Quality Control

Our 1-Methyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.