Description

Dimethyl(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Phosphine Oxide is a high-value, organoboron-containing phosphine oxide derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the synergistic reactivity of the boronic ester and phosphine oxide functional groups, enabling precise cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require sophisticated intermediates for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing complex biaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific boron- and phosphorus-containing motifs.
• Ligand Precursor: Serves as a starting material for synthesizing specialized phosphine ligands used in homogeneous catalysis.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the synthesis of electron-transport or host materials for advanced display technologies.
• Polymer Chemistry: Incorporated into monomers for creating specialty polymers with tailored thermal, optical, or mechanical properties.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Product Name	Dimethyl(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Phosphine Oxide
CAS No.	1394346-20-3
Molecular Formula	C14H22BO3P
Molecular Weight	280.11 g/mol
Synonyms	(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)dimethylphosphine oxide; Dimethyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]phosphine oxide; 2-[4-(Dimethylphosphinyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Dimethylphosphoryl)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Dimethyl(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Phosphine Oxide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analysis, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.