Description

2-Bromo-4-Fluoro-5-Iodobenzotrifluoride is a high-value, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, iodine, and a trifluoromethyl group, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting fluorine-containing drug candidates.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the halogen pattern can influence bioactivity and environmental stability.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as OLEDs and semiconductors, where the halogens facilitate cross-coupling reactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, leveraging the iodine and bromine sites for functionalization.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for imaging and diagnostic applications due to its reactive halogen handles.
• Custom Synthesis and R&D: An essential reagent for contract research organizations (CROs) and academic laboratories engaged in exploratory synthetic chemistry.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-Iodobenzotrifluoride
CAS No.	1394291-55-4
Molecular Formula	C7H2BrF4I
Molecular Weight	398.90 g/mol
Synonyms	1-Bromo-2-fluoro-4-iodo-5-(trifluoromethyl)benzene; 2-Bromo-4-fluoro-1-iodo-5-(trifluoromethyl)benzene; 5-Bromo-3-fluoro-4-iodobenzotrifluoride; Benzene, 1-bromo-2-fluoro-4-iodo-5-(trifluoromethyl)-; 2-Bromo-4-fluoro-5-iodo-α,α,α-trifluorotoluene; Halogenated Benzotrifluoride Intermediate
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Fluoro-5-Iodobenzotrifluoride is manufactured and tested under strict quality management protocols to ensure consistency and purity for critical R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (typically by HPLC/NMR), identity confirmation, and impurity profiles. Our quality systems are designed to support cGMP and ISO-guided workflows as required by our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.