Description

(E)-4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Styryl)Benzoic Acid is a high-value, functionalized organic building block featuring a benzoic acid group and a protected boronic ester moiety. This compound matters for its dual functionality, enabling precise cross-coupling reactions and subsequent derivatization in advanced material synthesis. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides through targeted biaryl bond formation.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in OLEDs, OFETs, and organic photovoltaics.
• Liquid Crystal & Dye Manufacturing: Employed in the synthesis of functional dyes and liquid crystal compounds due to its rigid, planar stilbene-like core.
• Metal-Organic Framework (MOF) Linker: The benzoic acid group allows for coordination with metal ions to construct novel porous materials for gas storage or catalysis.
• Polymer Modification: Used to introduce boronate ester or carboxylic acid functionalities into polymer backbones for specialty polymers.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of sensors or imaging agents.
• Academic & Contract Research: A valuable reagent for methodological development in synthetic organic chemistry and catalysis research.

Basic Information

Item	Details
Product Name	(E)-4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Styryl)Benzoic Acid
CAS No.	1394005-03-8
Molecular Formula	C21H23BO4
Molecular Weight	350.22 g/mol
Synonyms	4-[(1E)-2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethenyl]benzoic acid; (E)-4-[2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]vinyl]benzoic acid; (E)-4-(4-(Pinacolboryl)styryl)benzoic acid; 4-[(E)-2-(4-Pinacolatoboronphenyl)vinyl]benzoic acid; (E)-4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)styryl)benzoic acid; Boronic acid, B-[4-[(1E)-2-(4-carboxyphenyl)ethenyl]phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; CAS 1394005-03-8
EINECS	Contact for details

Quality Control

Our (E)-4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Styryl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.