Description

Lithium (6-(1,3-Dioxolan-2-Yl)Pyridin-2-Yl)Trihydroxyborate is a specialized organoboron reagent featuring a protected aldehyde functionality. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, particularly in cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial boronic ester reagent for forming carbon-carbon bonds between pyridine derivatives and various aryl/heteroaryl halides.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized bipyridine or terpyridine cores.
• Ligand Synthesis: Acts as a building block for creating sophisticated polydentate ligands used in catalysis and materials science.
• Agrochemical Research: Employed in the development of novel crop protection agents and herbicides.
• Material Science Precursor: Utilized in the preparation of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules for studying biological processes.

Basic Information

Product Name	Lithium (6-(1,3-Dioxolan-2-Yl)Pyridin-2-Yl)Trihydroxyborate
CAS No.	1393822-99-5
Molecular Formula	C8H11BLiO5
Molecular Weight	204.92 g/mol
Synonyms	Lithium (6-(1,3-Dioxolan-2-yl)pyridin-2-yl)trihydroborate; 2-(1,3-Dioxolan-2-yl)-6-pyridinylboronic acid lithium salt; Lithium 2-(1,3-dioxolan-2-yl)pyridine-6-boronate; 6-(1,3-Dioxolan-2-yl)pyridine-2-boronic acid lithium salt; 2-(1,3-Dioxolan-2-yl)-6-pyridylboronic acid lithium salt; Lithium [6-(1,3-dioxolan-2-yl)-2-pyridyl]trihydroxyborate; Boronic acid, B-[6-(1,3-dioxolan-2-yl)-2-pyridinyl]-, lithium salt (1:1)
EINECS	Contact for details

Quality Control

Our Lithium (6-(1,3-Dioxolan-2-Yl)Pyridin-2-Yl)Trihydroxyborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept under an inert atmosphere (argon or nitrogen) after opening and protected from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤2.0%
Solubility	Soluble in THF, DMF, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.