Description

Lithium (6-Methylpyridin-2-Yl)Trihydroxyborate is a specialized organoboron reagent featuring a lithium-borate complex with a methyl-substituted pyridine ligand. This compound matters as a highly versatile building block and catalyst precursor in advanced synthetic chemistry, enabling precise carbon-boron bond formation. It is primarily needed by research institutions and pharmaceutical companies engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable and effective organoboron reagent for constructing biaryl and heterobiaryl structures, crucial in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Serves as a key precursor in the multi-step synthesis of complex drug candidates, particularly those containing pyridine and boronic ester motifs.
• Agrochemical Research & Development: Used in creating novel herbicides, fungicides, and insecticides that require specific boron-containing heterocycles.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and electron-transport materials for optoelectronic devices.
• Catalyst & Ligand Preparation: Functions as a precursor for generating novel N,B-chelating ligands used in homogeneous catalysis.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes for studying biological processes via boron-based tagging or sensing.

Basic Information

Product Name	Lithium (6-Methylpyridin-2-Yl)Trihydroxyborate
CAS No.	1393822-95-1
Molecular Formula	C6H9BBLiNO3
Molecular Weight	163.91 g/mol
Synonyms	Lithium 6-Methylpyridin-2-yltrihydroborate; 2-(6-Methyl-2-pyridinyl)-1,3,2-dioxaborolane lithium salt (derivative); 6-Methyl-2-pyridineboronic acid lithium salt; Lithium (6-methyl-2-pyridyl)boronate; (6-Methylpyridin-2-yl)lithium trihydroborate; Borate(1-), trihydro(6-methyl-2-pyridinyl)-, lithium; Lithium trihydro(6-methyl-2-pyridinyl)borate(1-)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results, including assay by NMR or titration and impurity profiles, are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and tendency to be easily oxidized (store under inert atmosphere), this material should be stored under an inert gas (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (NMR/Titration)	≥95%
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.