Description

Lithium (5-Bromopyridin-2-Yl)Trihydroxyborate is a high-purity organoboron reagent, specifically a lithium borate complex, designed for advanced synthetic chemistry. This compound is a critical building block in modern cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds with high selectivity and yield. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key organoboron reagent for coupling with aryl/heteroaryl halides to construct biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research, development, and scale-up of drug candidates, particularly those containing functionalized pyridine motifs.
• Agrochemical Compound Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific bromopyridine-based architectures.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and material science applications.
• Organic Electronic Materials: A building block for creating conjugated organic molecules used in OLEDs, organic photovoltaics, and other advanced materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and complex molecular structures.

Basic Information

Product Name	Lithium (5-Bromopyridin-2-Yl)Trihydroxyborate
CAS No.	1393822-90-6
Molecular Formula	C5H6BBrLiNO3
Molecular Weight	217.88 g/mol
Synonyms	Lithium (5-Bromo-2-pyridyl)trihydroxyborate; 5-Bromo-2-pyridineboronic acid lithium salt; (5-Bromopyridin-2-yl)boronic acid lithium salt; 2-Pyridineboronic acid, 5-bromo-, lithium salt (1:1); Lithium 5-bromopyridine-2-boronate; 5-Bromo-2-pyridylboronic acid lithium complex; Boronic acid, B-(5-bromo-2-pyridinyl)-, lithium salt; 5-Bromopyridine-2-boronic acid lithium salt
EINECS	Contact for details

Quality Control

Our Lithium (5-Bromopyridin-2-Yl)Trihydroxyborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.