Description

1-(5-Bromo-3-Hydroxypyridin-2-Yl)Ethanone is a high-purity brominated pyridinone derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a bromo and a hydroxypyridinone moiety, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used as a precursor in the development of new herbicides and fungicides with specific modes of action.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other metal-catalyzed transformations to introduce complex heterocyclic systems.
• Ligand & Catalyst Development: The hydroxypyridinone group can act as a chelating ligand for metal complexes used in catalysis.
• Life Science Research: Used as a biochemical tool compound for probing biological pathways and enzyme functions.

Basic Information

Item	Details
Product Name	1-(5-Bromo-3-Hydroxypyridin-2-Yl)Ethanone
CAS No.	1393567-59-3
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	2-Acetyl-5-bromo-3-hydroxypyridine; 5-Bromo-3-hydroxy-2-acetylpyridine; 1-(5-Bromo-3-hydroxypyridin-2-yl)ethan-1-one; Ethanone, 1-(5-bromo-3-hydroxy-2-pyridinyl)-; 5-Bromo-3-hydroxypyridin-2-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-3-Hydroxypyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.