Description

β,β-Difluoro-3-Methyl-Benzeneethanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a difluoroethylamine side chain attached to a methyl-substituted benzene ring, makes it a valuable precursor for introducing fluorine atoms into target molecules, a key strategy in modern pharmaceutical and agrochemical design. This compound is primarily utilized by research chemists and process development scientists in the life sciences sector for creating novel active ingredients with enhanced metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating fluorine into bioactive molecules to modulate their pharmacokinetic and pharmacodynamic properties.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where fluorine atoms can improve lipophilicity, environmental stability, and target specificity.
• Ligand and Catalyst Development: Serves as a building block for constructing novel nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials, where fluorine can alter electronic properties and surface characteristics.
• Fluorine Chemistry Research: A valuable substrate for methodological studies in fluorination reactions and the exploration of new C-F bond forming transformations.

Basic Information

Product Name	β,β-Difluoro-3-Methyl-Benzeneethanamine
CAS No.	1393540-47-0
Molecular Formula	C9H11F2N
Molecular Weight	171.19 g/mol
Synonyms	2-(3-Methylphenyl)-2,2-difluoroethanamine; 1-(3-Methylphenyl)-2,2-difluoroethanamine; 3-Methyl-α,α-difluorophenethylamine; β,β-Difluoro-3-methylphenethylamine; 2,2-Difluoro-2-(3-methylphenyl)ethanamine; (3-Methylphenyl)difluoroethylamine; DFMPEA (abbreviation)
EINECS	Contact for details

Quality Control

Our β,β-Difluoro-3-Methyl-Benzeneethanamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles determined by validated analytical methods (HPLC, GC, NMR). Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider maintaining the material under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.