Description

Methyl 5-Nitro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate CAS NO 1393477-19-4 is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions that form carbon-carbon bonds. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides by constructing specific aromatic frameworks.
• Material Science: Building block for organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Synthesis: Versatile reagent for introducing functionalized benzoate groups into target molecules under mild conditions.
• Academic & R&D: Essential for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	Methyl 5-Nitro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1393477-19-4
Molecular Formula	C14H18BNO6
Molecular Weight	307.11 g/mol
Synonyms	Methyl 5-Nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Borono-5-nitrobenzoic Acid Methyl Ester, Pinacol Ester; 5-Nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Methyl Ester; Methyl 2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-5-nitrobenzoate (related structure); 1393477-19-4; Aryl Boronic Ester Pinacol; (5-Nitro-2-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzoate)
EINECS	Contact for details

Quality Control

Our Methyl 5-Nitro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.