Description

Methyl 2-Fluoro-5-(4-Formylphenyl)Benzoate is a high-purity, multi-functional aromatic ester building block designed for advanced synthetic chemistry. This compound is valued for its unique molecular architecture, incorporating both a reactive formyl group and a fluorinated benzoate moiety, which enables precise structural modifications. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-inflammatory agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a sophisticated building block for creating advanced organic electronic materials, where the fluorine and formyl groups help fine-tune electronic properties and molecular alignment.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions due to the presence of the halogenated aromatic ring.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functionalized materials, where it can act as a monomer or a post-polymerization modification agent.
• Chemical Biology & Probe Development: Useful for creating fluorescent probes, affinity labels, and other tools for studying biological systems, as the formyl group allows for facile conjugation.

Basic Information

Product Name	Methyl 2-Fluoro-5-(4-Formylphenyl)Benzoate
CAS No.	1393442-20-0
Molecular Formula	C15H11FO3
Molecular Weight	258.25 g/mol
Synonyms	Methyl 2-Fluoro-5-(4-formylphenyl)benzoate; 4'-(Methoxycarbonyl)-6-fluorobiphenyl-4-carboxaldehyde; 2-Fluoro-5-(4-formylphenyl)benzoic Acid Methyl Ester; Methyl 2-Fluoro-5-(4-formylphenyl)benzoate; 6-Fluoro-4'-formylbiphenyl-3-carboxylic Acid Methyl Ester; 4-(Methoxycarbonyl)-3-fluorobiphenyl-4'-carboxaldehyde; Methyl 5-(4-Formylphenyl)-2-fluorobenzoate; 3-Fluoro-4'-(methoxycarbonyl)biphenyl-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-5-(4-Formylphenyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.