Description

Bromo-Peg6-T-Butyl Ester CAS NO 1393330-41-0 is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a reactive bromo group and a protected carboxylic acid (t-butyl ester). This compound is a critical building block in bioconjugation and pharmaceutical development, enabling the precise modification and functionalization of biomolecules, polymers, and surfaces. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for creating targeted drug delivery systems, diagnostic agents, and functional biomaterials.

Application

• Bioconjugation Linker: Used to attach drugs, peptides, or fluorescent dyes to antibodies, proteins, or nanoparticles for targeted therapies and diagnostics.
• PEGylation Reagent: Serves as a functional spacer arm to introduce PEG chains onto active molecules, improving solubility, stability, and pharmacokinetics.
• Polymer Synthesis: Acts as a versatile monomer or initiator in the synthesis of functionalized, biocompatible polymers and hydrogels.
• Surface Modification: Employed to functionalize solid surfaces (e.g., gold, silica) with reactive groups for biosensor and microarray development.
• Intermediate for PROTACs & ADC: A key synthetic intermediate in the production of complex molecules like Proteolysis Targeting Chimeras (PROTACs) and Antibody-Drug Conjugates (ADCs).
• Crosslinking Agent: Used in the formation of crosslinked networks for controlled-release drug delivery systems.

Basic Information

Product Name	Bromo-Peg6-T-Butyl Ester
CAS No.	1393330-41-0
Molecular Formula	C21H41BrO9
Molecular Weight	517.45 g/mol
Synonyms	1-Bromo-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid tert-butyl ester; tert-Butyl 1-bromo-3,6,9,12,15,18-hexaoxahenicosan-21-oate; Br-PEG6-t-butyl ester; Bromo-PEG6-acid t-butyl ester; Bromo-PEG6-tBu ester; Bromo-PEG6-COOtBu; 2-[2-[2-[2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid tert-butyl ester; Bromohexaethylene glycol t-butyl ester
EINECS	Contact for details

Quality Control

Our Bromo-Peg6-T-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your research and cGMP-compliant development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.