Description

N,2-Dimethyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a specialized organoboron building block of significant importance in modern synthetic chemistry. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, enabling the construction of complex biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the boronate ester functionality allows for efficient carbon-carbon bond formation.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its ability to introduce functional aromatic amines.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling, a cornerstone reaction for forming carbon-carbon bonds between aryl and vinyl groups.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Used to create tagged molecules and probes for studying biological processes and protein interactions.

Basic Information

Product Name	N,2-Dimethyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1392846-26-2
Molecular Formula	C14H22BNO2
Molecular Weight	247.14 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,2-dimethylaniline; 2-Methyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanamine; N,2-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,2-dimethylaniline; N,2-Dimethyl-4-boronic acid pinacol ester aniline
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all relevant specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.