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3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenemethanol CAS NO 1392421-83-8


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CAS No.:1392421-83-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenemethanol is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing new active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and CNS-active compounds.
  • Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the boronate functional group for selective bond formation.
  • Liquid Crystal & OLED Materials: Serves as a building block for creating complex organic molecules used in electronic displays and lighting technologies.
  • Polymer & Resin Modification: Incorporated into specialty polymers to introduce functional groups that alter material properties like adhesion, solubility, or thermal stability.
  • Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological processes and diagnostics.
  • Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name 3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenemethanol
CAS No. 1392421-83-8
Molecular Formula C14H21BO4
Molecular Weight 264.13 g/mol
Synonyms [3-(Hydroxymethyl)-5-methoxyphenyl]boronic acid pinacol ester; 5-(Hydroxymethyl)-3-methoxybenzeneboronic acid pinacol ester; (3-(Hydroxymethyl)-5-methoxyphenyl)boronic acid pinacol ester; 3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl alcohol; Pinacol [3-(hydroxymethyl)-5-methoxyphenyl]boronate; 1392421-83-8; Boronic acid, B-[3-(hydroxymethyl)-5-methoxyphenyl]-, 1,1-dimethylethyl ester
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Quality Control

Every batch of 3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenemethanol is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical-grade material meets the rigorous demands of process chemistry and scale-up. A detailed Certificate of Analysis (COA) with batch-specific data from HPLC, NMR, and GC is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥97.0%
Purity (GC) ≥98.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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