Description

Potassium Tetrahydrofuran-3-Trifluoroborate is a high-purity organoboron reagent, specifically a potassium trifluoroborate salt. This compound is a valuable and stable synthetic intermediate, prized for its enhanced stability and handling properties compared to traditional boronic acids. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for key carbon-carbon bond-forming reactions, such as Suzuki-Miyaura cross-couplings.

Application

• Pharmaceutical Intermediate Synthesis: A key building block in the research and development of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the synthesis of novel compounds for crop protection and herbicide development.
• Materials Science: Employed in the creation of organic electronic materials, including polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile handle for bioconjugation and the synthesis of complex molecular probes.
• Process Chemistry & Scale-up: Its improved stability makes it suitable for optimizing and scaling synthetic routes from lab to pilot plant.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Potassium Tetrahydrofuran-3-Trifluoroborate
CAS No.	1391850-45-5
Molecular Formula	C4H7BF3KO
Molecular Weight	177.99 g/mol
Synonyms	Potassium 2,5-Dihydro-3-furanyltrifluoroborate; Potassium (2,5-Dihydrofuran-3-yl)trifluoroborate; 3-(Trifluoroborato)-2,5-dihydrofuran Potassium Salt; Tetrahydrofuran-3-yltrifluoroborate Potassium Salt; 2,5-Dihydro-3-furanyltrifluoroboronic Acid Potassium Salt; 3-Trifluoroboratotetrahydrofuran Potassium Salt; Potassium 3-Trifluoroboratotetrahydrofuran
EINECS	Contact for details

Quality Control

Our Potassium Tetrahydrofuran-3-Trifluoroborate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹¹B, ¹³C), HPLC, and elemental analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) and in a desiccator for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
¹¹B NMR Purity	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.