Description

Butanoic Acid, 3-Amino-4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester is a high-purity, protected amino acid derivative designed for advanced synthetic chemistry. This compound is a critical building block for the synthesis of complex peptides and other biologically active molecules, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development, where reliable quality and consistent supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Chemical Biology Research: Employed in the design and construction of molecular probes and tools for studying biological pathways.
• Agrochemical Development: Acts as an intermediate in the research and production of advanced crop protection agents.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	Butanoic Acid, 3-Amino-4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester
CAS No.	1391209-85-0
Molecular Formula	C11H20N2O5
Molecular Weight	260.29 g/mol
Synonyms	3-Amino-4-[(tert-butoxycarbonyl)amino]butanoic acid methyl ester; Methyl 3-amino-4-[(tert-butoxycarbonyl)amino]butanoate; Boc-Dab(OMe)-OH; (S)-Methyl 3-amino-4-((tert-butoxycarbonyl)amino)butanoate; 4-[(tert-Butoxycarbonyl)amino]-3-aminobutanoic acid methyl ester; 3-Amino-4-(Boc-amino)butyric acid methyl ester; Methyl 4-(Boc-amino)-3-aminobutyrate
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 3-Amino-4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Optical Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.