Description

5-[4-(Trifluoromethyl)Phenyl]Morpholin-3-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the morpholinone scaffold and the electron-withdrawing trifluoromethylphenyl group, which is instrumental in modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel small molecule drug candidates, particularly in central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the design and synthesis of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Acts as a precursor for specialty monomers or ligands in the development of advanced polymers and functional materials.
• Chemical Biology Probe Development: Employed as a building block to create tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	5-[4-(Trifluoromethyl)Phenyl]Morpholin-3-One
CAS No.	1391087-84-5
Molecular Formula	C11H10F3NO2
Molecular Weight	245.20 g/mol
Synonyms	5-[4-(Trifluoromethyl)phenyl]-3-morpholinone; 5-(4-Trifluoromethylphenyl)morpholin-3-one; 3-Morpholinone, 5-[4-(trifluoromethyl)phenyl]-; 5-(4-(Trifluoromethyl)phenyl)morpholin-3-one; 1391087-84-5; 5-(p-Trifluoromethylphenyl)morpholin-3-one; 5-(4-Trifluoromethylphenyl)-3-morpholinone
EINECS	Contact for details

Quality Control

Our 5-[4-(Trifluoromethyl)Phenyl]Morpholin-3-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.