Description

5-Hydroxy Thiabendazole-13C2,15N Methyl Ether Hydrochloride is a stable isotope-labeled derivative of the broad-spectrum anthelmintic and fungicide, thiabendazole. This compound is specifically designed for use as an internal standard in advanced analytical techniques, providing unmatched accuracy and reliability for quantitative analysis. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental monitoring sectors who require precise measurement of thiabendazole and its metabolites.

Application

• Internal Standard for LC-MS/MS and GC-MS: Primary application as a quantitative reference standard in mass spectrometry for accurate determination of thiabendazole residues.
• Pharmaceutical Metabolism and Pharmacokinetic (PK) Studies: Enables precise tracking and quantification of drug metabolites in biological matrices during ADME (Absorption, Distribution, Metabolism, and Excretion) research.
• Food Safety and Regulatory Testing: Critical for the accurate analysis of pesticide residues in fruits, vegetables, and other agricultural commodities to ensure compliance with global MRLs (Maximum Residue Limits).
• Environmental Monitoring: Used in the analysis of soil and water samples to monitor environmental contamination and degradation pathways of thiabendazole.
• Method Development and Validation: Serves as a key component in developing, optimizing, and validating new analytical methods for thiabendazole detection.
• Quality Control in API Manufacturing: Supports impurity profiling and assay verification in the production of active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	5-Hydroxy Thiabendazole-13C2,15N Methyl Ether Hydrochloride
CAS No.	1391054-13-9
Molecular Formula	C12H9D3N2OS • HCl (Note: Formula reflects deuterated positions; core structure is C12H913C215N2OS • HCl)
Molecular Weight	Contact for details
Synonyms	5-(Methoxy-13C)-Thiabendazole-15N Hydrochloride; [13C2,15N]-5-Methoxy Thiabendazole HCl; Thiabendazole-13C2,15N-5-methyl ether hydrochloride; 2-(4-Methoxy-13C-phenyl)-1H-benzimidazole-15N Hydrochloride; 5-Methoxybenzimidazole-13C2,15N Hydrochloride (related); Isotopically Labeled Thiabendazole Metabolite Standard; [13C,15N] TBZ-OH Methyl Ether HCl
EINECS	Contact for details

Quality Control

Our 5-Hydroxy Thiabendazole-13C2,15N Methyl Ether Hydrochloride is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for chemical purity and MS for isotopic enrichment verification, to ensure it meets the exacting standards required for analytical reference materials. A detailed Certificate of Analysis (COA) providing batch-specific data on purity, isotopic abundance, and other critical parameters is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 99 atom % 15N
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.