Description

Methanesulfonothioic Acid S1,S1'-1,3-(2,2-Difluoropropanediyl) Ester is a specialized organosulfur and organofluorine compound that serves as a critical building block in advanced chemical synthesis. Its unique bifunctional structure, featuring both sulfonothioate and difluoromethylene groups, makes it a valuable reagent for introducing specific functionalities into target molecules. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoromethylene group can improve lipophilicity and biological activity.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers with specific sulfur or fluorine-based properties.
• Ligand and Catalyst Development: Serves as a building block for creating novel ligands in coordination chemistry and organometallic catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Methanesulfonothioic Acid S1,S1'-1,3-(2,2-Difluoropropanediyl) Ester
CAS No.	1391052-77-9
Molecular Formula	C5H8F2O4S2
Molecular Weight	234.24 g/mol
Synonyms	1,3-Bis(methanesulfonothioyloxy)-2,2-difluoropropane; 2,2-Difluoropropane-1,3-diyl bis(methanesulfonothioate); Bis(methanesulfonothioic acid) 2,2-difluoropropanediyl ester; Difluoropropanediyl dimethanesulfonothioate; Propanediyldimethanesulfonothioic acid, 2,2-difluoro-; (2,2-Difluoropropane-1,3-diyl) dimethanesulfonothioate
EINECS	Contact for details

Quality Control

Every batch of Methanesulfonothioic Acid S1,S1'-1,3-(2,2-Difluoropropanediyl) Ester is manufactured and tested under a strict quality management system. We ensure high chemical purity and lot-to-lot consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.