Description

3-Fluoro-5-Trifluoromethoxy-Dl-Phenylalanine, 97% is a non-natural, fluorinated derivative of the amino acid phenylalanine, distinguished by its unique trifluoromethoxy and fluorine substituents. This compound serves as a critical high-purity building block for medicinal chemistry and advanced materials research, enabling the modulation of biological activity and physicochemical properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active compounds and ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in oncology and CNS disorders.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, where the fluorine and trifluoromethoxy groups enhance bioavailability and stability.
• Peptide Modification: Incorporated into synthetic peptides to study structure-activity relationships (SAR) and improve metabolic stability.
• Ligand Synthesis for Catalysis: Serves as a precursor for creating specialized ligands used in asymmetric synthesis and transition metal catalysis.
• Biochemical Probe Development: Utilized in the design of molecular probes and inhibitors for enzyme and receptor studies.
• Material Science: Acts as a monomer or functional additive in the development of advanced polymers with specific optical or surface properties.

Basic Information

Product Name	3-Fluoro-5-Trifluoromethoxy-Dl-Phenylalanine, 97%
CAS No.	1391002-18-8
Molecular Formula	C₁₀H₉F₄NO₃
Molecular Weight	267.18 g/mol
Synonyms	DL-3-Fluoro-5-(trifluoromethoxy)phenylalanine; (±)-2-Amino-3-[3-fluoro-5-(trifluoromethoxy)phenyl]propanoic acid; 3-Fluoro-5-trifluoromethoxy-DL-phenylalanine; F-TFM-Phe; 3-F-5-TFM-Phe; α-Amino-3-fluoro-5-(trifluoromethoxy)benzenepropanoic acid (racemic)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Trifluoromethoxy-Dl-Phenylalanine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure the specified purity and identity. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.