Description

2-Oxo-3-Oxa-1,9-Diaza-Spiro[5.5]Undecane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel, complex drug candidates. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary active pharmaceutical ingredients (APIs) with spirocyclic architectures.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new biological leads.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the synthesis of linker components or warhead ligands for targeted protein degradation therapeutics.
• CNS Drug Discovery: Employed in the research and development of novel neuroactive compounds due to the favorable physicochemical properties often associated with spiro structures.
• Oncology Research: Utilized as a building block for kinase inhibitors and other targeted cancer therapies requiring complex heterocyclic cores.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and process development.

Basic Information

Product Name	2-Oxo-3-Oxa-1,9-Diaza-Spiro[5.5]Undecane
CAS No.	1389264-24-7
Molecular Formula	C8H13N3O2
Molecular Weight	183.21 g/mol
Synonyms	1,9-Diaza-2-oxo-3-oxaspiro[5.5]undecane; 3-Oxa-1,9-diaza-2-oxospiro[5.5]undecane; 2-Oxo-3-oxa-1,9-diazaspiro[5.5]undecane; Spiro[5.5]undecane-2-one, 3-oxa-1,9-diaza-; 1389264-24-7; 2-Oxo-3-oxa-1,9-diazaspiro[5.5]undecane; 1,9-Diazaspiro[5.5]undecane-2-one, 3-oxa-
EINECS	Contact for details

Quality Control

Our 2-Oxo-3-Oxa-1,9-Diaza-Spiro[5.5]Undecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.