Description

Ethanone, 1-(3-Bromo-2,6-Difluorophenyl)- is a high-purity, halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Acts as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials that benefit from its specific halogen substitution pattern.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Fluorine Chemistry Research: A valuable substrate for studying the influence of fluorine atoms on reaction kinetics, metabolic stability, and lipophilicity in medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Ethanone, 1-(3-Bromo-2,6-Difluorophenyl)-
CAS No.	1387634-87-8
Molecular Formula	C8H5BrF2O
Molecular Weight	235.03 g/mol
Synonyms	1-(3-Bromo-2,6-difluorophenyl)ethanone; 3'-Bromo-2',6'-difluoroacetophenone; 3-Bromo-2,6-difluoroacetophenone; 2',6'-Difluoro-3'-bromoacetophenone; Acetophenone, 3'-bromo-2',6'-difluoro-; 1-Acetyl-3-bromo-2,6-difluorobenzene
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(3-Bromo-2,6-Difluorophenyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.