Description

4H-1-Benzopyran-4-One, 5-Fluoro- is a high-purity fluorinated benzopyranone derivative, a key synthetic intermediate valued for its role in constructing complex heterocyclic scaffolds. Its primary commercial value lies in enabling advanced research and development within the pharmaceutical and agrochemical sectors. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the areas of kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in oncology and CNS research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chemical Biology Probe Synthesis: Serves as a core structure for creating fluorescent probes or activity-based protein profiling (ABPP) reagents.
• Material Science Precursor: Potential intermediate for the synthesis of advanced organic electronic materials or specialty polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory chemistry.

Basic Information

Product Name	4H-1-Benzopyran-4-One, 5-Fluoro-
CAS No.	1386253-18-4
Molecular Formula	C9H5FO2
Molecular Weight	164.13 g/mol
Synonyms	5-Fluorochromone; 5-Fluoro-4H-chromen-4-one; 5-Fluoro-1-benzopyran-4-one; 5-Fluoro-4H-1-benzopyran-4-one; 5-Fluorochroman-4-one; Chromone, 5-fluoro-; 4H-Chromen-4-one, 5-fluoro-
EINECS	Contact for details

Quality Control

Our 4H-1-Benzopyran-4-One, 5-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.