Description

Benzonitrile, 2-(Methylamino)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional chemical building block featuring both a nitrile and a boronic ester pinacol group. This compound matters for its critical role as a key intermediate in modern synthetic chemistry, enabling efficient cross-coupling reactions to construct complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of new active ingredients and functional polymers. Its unique structure offers versatile reactivity for creating novel carbon-carbon and carbon-heteroatom bonds.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors, light-emitting materials, and advanced polymers with tailored electronic properties.
• Ligand & Catalyst Design: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: Essential for research institutions and CROs exploring new synthetic methodologies and novel compound libraries.

Basic Information

Item	Details
Product Name	Benzonitrile, 2-(Methylamino)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1384855-57-5
Molecular Formula	C14H19BN2O2
Molecular Weight	258.13 g/mol
Synonyms	2-(Methylamino)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 4-Borono-2-(methylamino)benzonitrile pinacol ester; (2-Cyano-5-(methylamino)phenyl)boronic acid pinacol ester; 2-Amino-5-cyanophenylboronic acid pinacol ester, N-methyl-; 2-Methylamino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(methylamino)benzonitrile; PINACOL [2-CYANO-5-(METHYLAMINO)PHENYL]BORONATE
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2-(Methylamino)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.