Description

2-(7-(tert-Butoxycarbonyl)-7-Azaspiro[3.5]Nonan-2-Yl)Acetic Acid is a high-value, protected amino acid derivative featuring a spirocyclic scaffold. This compound is a critical pharmaceutical intermediate and building block in advanced organic synthesis, prized for its structural complexity and functional handles for further derivatization. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including protease inhibitors and other bioactive molecules.

Application

• Key Intermediate in Drug Discovery: Serves as a sophisticated precursor in the synthesis of complex pharmacophores for targets in oncology, virology, and neurology.
• Peptidomimetic Synthesis: Used to construct spirocyclic peptide analogs, enhancing metabolic stability and binding affinity in drug candidates.
• Protease Inhibitor Development: The structural motif is valuable for creating inhibitors of various proteolytic enzymes.
• Chemical Biology Tool: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Advanced Material Research: Potential building block for specialty polymers and functionalized surfaces with specific chemical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial scale-up projects.

Basic Information

Product Name	2-(7-(tert-Butoxycarbonyl)-7-Azaspiro[3.5]Nonan-2-Yl)Acetic Acid
CAS No.	1384265-35-3
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	Boc-7-Azaspiro[3.5]nonane-2-acetic Acid; 2-[7-[(2-Methylpropan-2-yl)oxycarbonyl]-7-azaspiro[3.5]nonan-2-yl]acetic Acid; tert-Butyl 2-(carboxymethyl)-7-azaspiro[3.5]nonane-7-carboxylate; 7-(tert-Butoxycarbonyl)-7-azaspiro[3.5]nonane-2-acetic Acid; Boc-7-Azaspiro[3.5]nonan-2-ylacetic Acid; 1384265-35-3; Azaspirocyclic Boc-Protected Acid
EINECS	Contact for details

Quality Control

Our production of 2-(7-(tert-Butoxycarbonyl)-7-Azaspiro[3.5]Nonan-2-Yl)Acetic Acid adheres to stringent quality protocols suitable for pharmaceutical R&D. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, NMR, and mass spectrometry data are provided to guarantee the material meets your specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.