Description

{[5-Chloro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}Dimethylamine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its role in facilitating complex carbon-carbon bond formations, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new therapeutic agents and specialty chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron-containing reagent for constructing biaryl structures, a common motif in many pharmaceuticals and organic electronic materials.
• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific chlorinated biphenyl architectures.
• Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and polymers where precise molecular engineering is required.
• Chemical Biology & Medicinal Chemistry: Acts as a versatile probe or building block for creating compound libraries used in high-throughput screening and structure-activity relationship (SAR) studies.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligand systems for transition metal catalysis.

Basic Information

Product Name	{[5-Chloro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}Dimethylamine
CAS No.	1384216-47-0
Molecular Formula	C15H23BClNO2
Molecular Weight	295.61 g/mol
Synonyms	5-Chloro-2-((dimethylamino)methyl)phenylboronic acid pinacol ester; (5-Chloro-2-((dimethylamino)methyl)phenyl)boronic acid pinacol ester; N,N-Dimethyl-1-(5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine; 2-((Dimethylamino)methyl)-4-chlorophenylboronic acid pinacol ester; [5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]dimethylamine
EINECS	Contact for details

Quality Control

Our {[5-Chloro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}Dimethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.