Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indolin-2-One is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those containing indolinone or heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific boronic acid coupling steps.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, polymers, and liquid crystals.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and enzyme inhibitors for target identification and validation.
• Academic & R&D Laboratories: A standard reagent for methodological development in cross-coupling catalysis and synthetic route exploration.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals and complex fragrance or flavor molecules.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indolin-2-One
CAS No.	1383995-23-0
Molecular Formula	C15H20BNO3
Molecular Weight	273.14 g/mol
Synonyms	2-Oxo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indoline; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-indol-2-one; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one; 5-(Pinacolatoboryl)indolin-2-one; 5-(2-Oxoindolin-5-yl)boronic acid pinacol ester; 5-Boronopinacolate indolin-2-one; 1383995-23-0; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-indolinone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and supply reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.