Description

3-Iodo-2,5,6-Trimethoxyisonicotinaldehyde is a high-purity, multi-functional chemical building block featuring a reactive aldehyde group and halogenated pyridine core. This compound is valued for its versatility in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs), particularly for neurological and oncological targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated pyridine structure.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials, dyes, and photoactive compounds.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form new carbon-carbon bonds.
• Aldehyde Functionalization: The reactive formyl group allows for further derivatization through condensation, reduction, or nucleophilic addition reactions.

Basic Information

Product Name	3-Iodo-2,5,6-Trimethoxyisonicotinaldehyde
CAS No.	1383788-27-9
Molecular Formula	C9H10INO4
Molecular Weight	323.09 g/mol
Synonyms	2,5,6-Trimethoxy-3-iodoisonicotinaldehyde; 3-Iodo-2,5,6-trimethoxypyridine-4-carboxaldehyde; 4-Formyl-3-iodo-2,5,6-trimethoxypyridine; Isonicotinaldehyde, 3-iodo-2,5,6-trimethoxy-; 1383788-27-9; 3-Iodo-2,5,6-trimethoxy-4-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Iodo-2,5,6-Trimethoxyisonicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.