Description

Methyl2-(4-Chlorophenyl)-4-Oxo-4-Phenylbutanoate CAS NO 1383253-45-9 is a high-purity, non-racemic chiral building block and synthetic intermediate. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecules with defined stereochemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, or insecticides where specific stereochemistry is crucial for bioactivity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrances, flavors, or specialty performance chemicals.
• Academic & Institutional R&D: Utilized in university and government laboratories for methodological studies in synthetic organic chemistry and medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl2-(4-Chlorophenyl)-4-Oxo-4-Phenylbutanoate
CAS No.	1383253-45-9
Molecular Formula	C17H15ClO3
Molecular Weight	302.75 g/mol
Synonyms	Methyl 2-(4-Chlorophenyl)-4-oxo-4-phenylbutanoate; Methyl 4-Oxo-2-(4-chlorophenyl)-4-phenylbutyrate; 2-(4-Chlorophenyl)-4-oxo-4-phenylbutyric Acid Methyl Ester; (2R)-2-(4-Chlorophenyl)-4-oxo-4-phenylbutanoic Acid Methyl Ester (enantiomer); (2S)-2-(4-Chlorophenyl)-4-oxo-4-phenylbutanoic Acid Methyl Ester (enantiomer); Butanoic acid, 2-(4-chlorophenyl)-4-oxo-4-phenyl-, methyl ester; 1383253-45-9
EINECS	Contact for details

Quality Control

Our Methyl2-(4-Chlorophenyl)-4-Oxo-4-Phenylbutanoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, guaranteeing traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiomerically enriched grades)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.