Description

Methyl 2-Ethyl-2-(((4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Oxy)Methyl)Butanoate is a high-value, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is primarily sought by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science: Precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand Synthesis: Serves as a starting material for the preparation of sophisticated ligands used in catalysis.
• Chemical Biology Probes: Enables the labeling and study of biological targets through bioconjugation strategies.
• Academic & Contract Research: Essential reagent for methodology development and complex molecule synthesis in research laboratories.

Basic Information

Product Name	Methyl 2-Ethyl-2-(((4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Oxy)Methyl)Butanoate
CAS No.	1383002-31-0
Molecular Formula	C21H34BNO5
Molecular Weight	391.31 g/mol
Synonyms	2-Ethyl-2-(((4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)oxy)methyl)butanoic acid methyl ester; Methyl 2-ethyl-2-[[[4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]oxy]methyl]butanoate; Pinacol ester of (6-((1-(Methoxycarbonyl)-1-ethylpropoxy)methyl)-4-methylpyridin-3-yl)boronic acid; 1383002-31-0; Boronic ester pyridine derivative; Suzuki-Miyaura coupling reagent.
EINECS	Contact for details

Quality Control

Our Methyl 2-Ethyl-2-(((4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Oxy)Methyl)Butanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization including NMR (1H, 13C, 11B), HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) with full analytical data are provided to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize condensation and hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.