Description

tert-Butyl (2-Bromo-5-Formylpyridin-4-Yl)Carbamate is a high-purity, multi-functional pyridine derivative designed for advanced synthetic chemistry. This compound serves as a critical building block for the development of complex molecules, offering versatile reactivity at the bromo, formyl, and protected amine sites. It is primarily utilized by pharmaceutical and agrochemical R&D teams engaged in the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Synthesis: Serves as a starting material for constructing complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Chemical Biology Probes: Used to create labeled compounds and molecular probes for biochemical and diagnostic research.

Basic Information

Product Name	tert-Butyl (2-Bromo-5-Formylpyridin-4-Yl)Carbamate
CAS No.	1382849-21-9
Molecular Formula	C11H13BrN2O3
Molecular Weight	301.14 g/mol
Synonyms	Boc-4-Amino-2-bromo-5-formylpyridine; 4-[(tert-Butoxycarbonyl)amino]-2-bromo-5-pyridinecarboxaldehyde; 2-Bromo-5-formylpyridin-4-yl-carbamic acid tert-butyl ester; tert-Butyl N-(2-bromo-5-formyl-4-pyridyl)carbamate; 2-Bromo-4-(Boc-amino)-5-formylpyridine; 4-N-Boc-amino-2-bromo-5-formylpyridine; Boc-protected 2-bromo-5-formyl-4-aminopyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-Bromo-5-Formylpyridin-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.