Description

1-(5-Bromopyridin-2-Yl)Cyclobutanecarboxylic Acid is a high-value brominated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring a cyclobutane ring fused to a functionalized pyridine core, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the bromopyridine moiety can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional organic materials, such as liquid crystals or organic semiconductors.
• Chemical Biology Probes: Useful for creating tagged molecules or probes to study biological pathways and interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-(5-Bromopyridin-2-Yl)Cyclobutanecarboxylic Acid
CAS No.	1382486-27-2
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	1-(5-Bromo-2-pyridinyl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-(5-bromo-2-pyridinyl)-; 1-(5-Bromopyridin-2-yl)cyclobutanecarboxylic acid; 2-(5-Bromopyridin-2-yl)cyclobutanecarboxylic acid (tautomer); 5-Bromo-2-(1-carboxycyclobutyl)pyridine; 1382486-27-2
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromopyridin-2-Yl)Cyclobutanecarboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under inert atmosphere when possible and opened in a controlled, dry environment to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.