Description

4,4,5,5-Tetramethyl-2-[4-(4-Methylphenyl)Phenyl]-1,3,2-Dioxaborolane CAS NO 1381960-58-2 is a high-purity, advanced boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common structural motif in pharmaceuticals and organic materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for creating complex, sterically hindered biaryl structures.
• Agrochemical Development: Serves as a crucial precursor in the synthesis of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Polymer and Material Science: Incorporated into monomers for creating specialty polymers with tailored electronic or mechanical properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[4-(4-Methylphenyl)Phenyl]-1,3,2-Dioxaborolane
CAS No.	1381960-58-2
Molecular Formula	C19H23BO2
Molecular Weight	294.20 g/mol
Synonyms	2-[4-(p-Tolyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-ylmethane; 4-Methyl-[1,1'-biphenyl]-4-boronic acid pinacol ester; 4-(4-Methylphenyl)phenylboronic acid pinacol ester; p-Tolylphenylboronic acid pinacol ester; B-[4-(4-Methylphenyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[4-(4-Methylphenyl)Phenyl]-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.